How to treat wounds? The answer is in blood
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How to treat wounds?
The answer is in blood
How to treat wounds, without side effect with excellent results.
The answer it’s not far from us, but it should be inside us!
Leaving aside the metaphorical choice of words, the blood’s patient, can be the better solution for care of skin wounds. Let's find out how to treat dog wounds fast.
Skin has a crucial role in defense thanks to its self-repairing and self-renewing capacity, acting as an important barrier from the outer environment. A disturbance of the normal anatomic structure and functional integrity of the skin can be described as a wound and his healing is a complicated process mediated by physical, chemical, and cellular processes.
The healing process consist in a series of events that work to produce the formation of new connective tissue, so different from the original one. The process develops in different phasis, preceded by hemostasis and consists of inflammation, proliferation/repair, and remodeling.
The smooth running of this process il fondamental, cause if is interrupted, chronic wounds can appear, on the contrary, with an out control regulation of the processes of inflamation and cells proliferation, the risk is to obtain too much granulation tissue like cheloids.
Despite significant advances in medical care and nutrition, there is a growing need to develop novel strategies to improve cutaneous wound healing.
In human field as well as in veterinary field, Platelet-rich plasma (PRP) is an endogenous therapeutic technology that is gaining interest in regenerative medicine due to its potential to stimulate and accelerate tissue healing
PRP is defined as an autologous biological product derived from the patient’s blood with a platelet concentration higher than that in circulating blood.
The use of PRP
The platelets, in wich P.R.P. is rich, release many substances that promote tissue repair and affect the behaviour of others cells modulating inflamation and new formation of vessel.
Platelets infact, play a significant role in mediate the healing ao damaged tissue thanks to his ability to release growth factors involved in the wound healing process , such as
• platelet-derived growth factor (PDGF),
• epidermal growth factor (EGF),
• fibroblast growth factor (FGF),
• insulin-like growth factor (IGF1, IGF2),
• vascular endothelial growth factor (VEGF),
• transforming growth factor (TGF-β),
• and keratinocyte growth factor (KGF)
The use of PRP has had a potential impact in reducing economic costs for standard medical treatments, although it should not be considered as a therapy that replaces certain essential conventional treatments, but as a complementary therapy.
The use of PRP in both humans and animals is steadily increasing, and its healing properties in cutaneous wounds have been reported in many clinical and experimental studies with dogs[1;2], horses [1] humans[1; 2], and other spicies[1].
Il PRP is commonly applied to wounds in liquid form for injection, but this provokes irritation and pain because of high concentration of white blood cells. Sometime PRP is made in gel, this formulation is easy to use but ma has disadvantages, especially in animals,such as uneven distribution at movable body parts, possible loss, limited accessibility to the wound surface, and limited duration of effect.
What if there was a way?
Ematik Ready is a medical device that can meet the needs of veterinarians, creating a final product in a standard process, autologous because obtained by a blood collect.
The kit allows to create a patch made by a gel and a special biopolimeric mixture.
This mixture gives structure, stability and flexbility to the patch that can be applied on to wound, cuttable if you need, without material losses and durable in time, with controlled release of growth factors.
In veterinary field Ematik Ready represents the perfect method to produce a blood derivative to apply directly on the wound, guaranteeing constant yield and quality, as shown by our clinical cases.
At last doing the math, the high degree of asfety (has no side effects) and good results in literature in many fields of medicine, blood derivativess like PRP seem to be a new promise in terapies involving in tissue regeneration, both in human and animal fields.
Sources
https://www.centronazionalesangue.it/node/410
http://www.ior.it/laboratori/lab-di-biomec-inn-tec/Biotecnologie/utilizzo-del-prp
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872096/
https://www.avis.it/2019/02/15/plasma-ricco-di-piastrine-una-risorsa-per-molte-terapie/
